Category: Ion channels

Ion channels Journal Articles this Week

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Rectification of muscle and nerve deficits in paralyzed ryanodine receptor type 1 mutant embryos.

Locomotion and respiration require motor axon connectivity and activation of the neuromuscular…

Published: Jun 01, 2015 in Developmental Biology

Central serous chorioretinopathy: Recent findings and new physiopathology hypothesis.

Central serous chorioretinopathy (CSCR) is a major cause of vision threat among middle-aged male…

Published: Jun 01, 2015 in Progress in Retinal & Eye Research

A Fluorescent Approach for Identifying P2X1 Ligands.

There are no commercially available, small, receptor-specific P2X1 ligands. There are several…

Published: Jun 01, 2015 in Neuropharmacology

Human engineered heart tissue as a model system for drug testing.

Drug development is time- and cost-intensive and, despite extensive efforts, still hampered by the…

Published: Jun 01, 2015 in Advanced Drug Delivery Reviews

Accurate Encoding and Decoding by Single Cells: Amplitude Versus Frequency Modulation

Cells sense external concentrations and, via biochemical signaling, respond by regulating the…

Published: May 31, 2015 in PLoS Computational Biology

Ambulatory Blood Pressure in Untreated and Treated Hypertensive Patients at High Altitude: The High Altitude Cardiovascular Research-Andes Study.

Blood pressure increases during acute exposure to high altitude in healthy humans. However, little…

Published: May 31, 2015 in Hypertension (Highwire)

MicroRNA-1298 is regulated by DNA methylation and affects vascular smooth muscle cell function by targeting connexin 43.

Aims Growing evidence links microRNA to the process of peripheral vascular disease. Recently, we…

Published: May 31, 2015 in Cardiovascular Research

Desformylflustrabromine modulates α4β2 nAChR high- and low- sensitivity isoforms at allosteric clefts containing the β2 subunit.

Alterations in expression patterns of alpha4beta2 nicotinic acetylcholine receptors (nAChR) have…

Published: May 31, 2015 in The Journal of Pharmacology and Experimental Therapeutics

Whole Transcriptome of the Venom Gland from Urodacus yaschenkoi Scorpion.

Australian scorpion venoms have been poorly studied, probably because they do not pose an evident…

Published: May 27, 2015 in PLoS ONE

Alterations in late endocytic trafficking related to the pathobiology of LRRK2-linked Parkinson’s disease.

Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene comprise the most common cause of…

Published: May 27, 2015 in Biochemical Society Transactions

News Articles (Ion channels)

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Calcium Channel Blockers Don?t Promote Breast Cancer

(MedPage Today) -- Massive study finds no link between antihypertensive class and malignancy.

Published: Jun 02, 2015

Mutation in transient receptor potential channel impairs fine motor control but leaves gross motor proficiency intact

In all animals—from humans to fruit flies—coordinated physical movement relies on two…

Published: Jun 01, 2015

Preoperative statins reduce mortality in coronary artery bypass graft surgery

Research presented at this year's Euroanaesthesia exploring the protective effect of various heart…

Published: May 30, 2015

Rapid and cost-effective chromosomal phasing is possible with Droplet Digital PCR Technology

Researchers published a new method facilitating the study of how the distribution of mutations…

Published: May 28, 2015

Cavion to Present Clinical Trial Data at ASCO

CHARLOTTESVILLE, Va.--(BUSINESS WIRE)--Cavion and NCI ABTC to present Phase 1b clinical trial…

Published: May 28, 2015

Researchers stop brain swelling at the source in animal model.

A team of researchers have made a significant discovery in the mechanism of brain swelling, paving…

Published: May 27, 2015

Novel drug combo improves function of protein underlying cystic fibrosis

A novel two-drug combination has the potential to target and restore a defective protein underlying…

Published: May 27, 2015

Simple recipe to make sensory hair cells in the ear

Millions of people worldwide have permanent hearing and balance impairments due to damage to the…

Published: May 26, 2015

New antibody insecticide targets malaria mosquito

Malaria is a cruel and disabling disease that targets victims of all ages. Even now, it is estimated…

Published: May 20, 2015

What happens inside a membrane

(International School of Advanced Studies (SISSA)) Little is known about how the proteins forming…

Published: May 20, 2015

Blog Posts (Ion channels)

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Uncomfortably numb: The people who feel no pain

Researchers have identified a third gene that causes congenital insensitivity to pain when…

Published: May 25, 2015

Jobs (Ion channels)

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Postdoctoral Research Scientist with Expertise in Electrophysiology

University of Oxford - Nuffield Department of Clinical NeurosciencesSalary: Not specified

Posted: May 28, 2015