Category: Mitochondria

Mitochondria Journal Articles this Week

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Severe encephalopathy associated to pyruvate dehydrogenase mutations and unbalanced coenzyme Q10 content.

Coenzyme Q10 (CoQ10) deficiency is associated to a variety of clinical phenotypes including…

Published: May 26, 2015 in European Journal of Human Genetics

Compound heterozygous GFM2 mutations with Leigh syndrome complicated by arthrogryposis multiplex congenita.

Defects in the mitochondrial translation apparatus can impair energy production in affected tissues…

Published: May 27, 2015 in Journal of Human Genetics

Aggregation of rare/low-frequency variants of the mitochondria respiratory chain-related proteins in rheumatoid arthritis patients.

Exome sequencings were conducted using 59 patients having rheumatoid arthritis (RA) and 93 controls.…

Published: May 27, 2015 in Journal of Human Genetics

Fast-digestive protein supplement for ten days overcomes muscle anabolic resistance in healthy elderly men.

Adequate protein intake is crucial to maintain muscle protein content in elderly subjects, but…

Published: May 27, 2015 in Clinical Nutrition

Microbiota prevents cholesterol loss from the body by regulating host gene expression in mice.

We have previously observed that knockout of Niemann-Pick C1-Like 1 (NPC1L1), a cholesterol…

Published: May 28, 2015 in Scientific Reports

Loss of Function Mutations in NNT Are Associated with Left Ventricular Noncompaction.

-Left ventricular noncompaction (LVNC) is an autosomal dominant, genetically heterogeneous…

Published: May 31, 2015 in Circulation: Cardiovascular Genetics

Extensive Horizontal Transfer and Homologous Recombination Generate Highly Chimeric Mitochondrial Genomes in Yeast.

The frequency of horizontal gene transfer (HGT) in mitochondrial DNA varies substantially in plants,…

Published: May 29, 2015 in Molecular Biology and Evolution

Differential modulation of AMPK/PPARα/UCP2 axis in relation to hypertension and aging in the brain, kidneys and heart of two closely related spontaneously hypertensive rat strains.

We examined expression protein of AMPK/SIRT1/PGC1α/PhoxO3a/PPARα/UCP2 pathway in brain, kidneys…

Published: May 31, 2015 in Oncotarget

Combinatorial cancer immunotherapy strategies with proapoptotic small-molecule IAP antagonists.

Members of the inhibitor of apoptosis (IAP) family control several critical aspects of innate…

Published: May 27, 2015 in International Journal of Developmental Biology

News Articles (Mitochondria)

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POXEL Announces Successful Results for Imeglimin Phase 1 Study in Japanese Subjects and Appoints Dr. Yohjiro Itoh to Lead its Regulatory and Clinical Operations in Asia

LYON, France--(BUSINESS WIRE)--POXEL Announces Successful Results for Imeglimin Phase 1 Study in…

Published: May 27, 2015

Scientists reverse aging in human cell lines and give theory of aging a new lease of life

Can the process of aging be delayed or even reversed? Research led by specially appointed Professor…

Published: May 26, 2015

Oxidative stress is an aggravating factor in Lafora rare disease

Neurodegenerative Lafora disease usually becomes apparent through seizures during adolescence and…

Published: May 22, 2015

Researchers identify and correct premature aging in diseased cells.

Scientists from the Institut Pasteur, CNRS, Institut Gustave Roussy and CEA, have succeeded in…

Published: May 22, 2015

Premature aging: Scientists identify and correct defects in diseased cells

(Institut Pasteur) Scientists from the Institut Pasteur and CNRS, in collaboration with scientists…

Published: May 21, 2015

New cryptic amphipod discovered in West Caucasus caves

An international team of scientists have discovered a new species of typhlogammarid amphipod in the…

Published: May 18, 2015

UCLA researchers deliver large particles into cells at high speed

UCLA engineers and doctors developed a tool that can deliver nanoparticles, enzymes, antibodies and…

Published: Apr 08, 2015

Rare cause of anemia in newborns often overlooked, research suggests

Some babies diagnosed with and treated for a bone marrow failure disorder, called Diamond Blackfan…

Published: Dec 07, 2013

New tool determines leukemia cells’ ‘readiness to die,’ may guide clinical care

Dana-Farber researchers have developed a method for determining how ready acute myeloid leukemia…

Published: Oct 11, 2012

Dana-Farber Cancer Institute scientists target newly isolated ‘beige fat’ cells that could help fight obesity

Dana-Farber Cancer Institute researchers have isolated a new type of energy-burning fat cell called…

Published: Jul 12, 2012

Blog Posts (Mitochondria)

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A Dunning-Kruger manifesto about vaccines and autism [Respectful Insolence]

I’ve frequently written about the “arrogance of ignorance,” a phenomenon that…

Published: May 29, 2015

Jobs (Mitochondria)

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Assistant Professor in Mitochondrial Biology and Metabolic Diseases

Max Planck Institute for Biology of Ageing – Karolinska Institutet Laboratory The newly…

Posted: May 29, 2015