Mitochondria Journal Articles this Week
Severe encephalopathy associated to pyruvate dehydrogenase mutations and unbalanced coenzyme Q10 content.
Coenzyme Q10 (CoQ10) deficiency is associated to a variety of clinical phenotypes including…Published: May 26, 2015 in European Journal of Human Genetics
Compound heterozygous GFM2 mutations with Leigh syndrome complicated by arthrogryposis multiplex congenita.
Defects in the mitochondrial translation apparatus can impair energy production in affected tissues…Published: May 27, 2015 in Journal of Human Genetics
Aggregation of rare/low-frequency variants of the mitochondria respiratory chain-related proteins in rheumatoid arthritis patients.
Exome sequencings were conducted using 59 patients having rheumatoid arthritis (RA) and 93 controls.…Published: May 27, 2015 in Journal of Human Genetics
Fast-digestive protein supplement for ten days overcomes muscle anabolic resistance in healthy elderly men.
Adequate protein intake is crucial to maintain muscle protein content in elderly subjects, but…Published: May 27, 2015 in Clinical Nutrition
We have previously observed that knockout of Niemann-Pick C1-Like 1 (NPC1L1), a cholesterol…Published: May 28, 2015 in Scientific Reports
Hurt, tired and queasy: Specific variants in the ATPase domain of the TRAP1 mitochondrial chaperone are associated with common, chronic “functional” symptomatology including pain, fatigue and gastrointestinal dysmotility.
Functional disorders are common conditions with a substantial impact on a patients' wellbeing, and…Published: May 30, 2015 in Mitochondrion
-Left ventricular noncompaction (LVNC) is an autosomal dominant, genetically heterogeneous…Published: May 31, 2015 in Circulation: Cardiovascular Genetics
Extensive Horizontal Transfer and Homologous Recombination Generate Highly Chimeric Mitochondrial Genomes in Yeast.
The frequency of horizontal gene transfer (HGT) in mitochondrial DNA varies substantially in plants,…Published: May 29, 2015 in Molecular Biology and Evolution
Differential modulation of AMPK/PPARα/UCP2 axis in relation to hypertension and aging in the brain, kidneys and heart of two closely related spontaneously hypertensive rat strains.
We examined expression protein of AMPK/SIRT1/PGC1α/PhoxO3a/PPARα/UCP2 pathway in brain, kidneys…Published: May 31, 2015 in Oncotarget
Members of the inhibitor of apoptosis (IAP) family control several critical aspects of innate…Published: May 27, 2015 in International Journal of Developmental Biology
News Articles (Mitochondria)
POXEL Announces Successful Results for Imeglimin Phase 1 Study in Japanese Subjects and Appoints Dr. Yohjiro Itoh to Lead its Regulatory and Clinical Operations in Asia
LYON, France--(BUSINESS WIRE)--POXEL Announces Successful Results for Imeglimin Phase 1 Study in…Published: May 27, 2015
Scientists reverse aging in human cell lines and give theory of aging a new lease of life
Can the process of aging be delayed or even reversed? Research led by specially appointed Professor…Published: May 26, 2015
Oxidative stress is an aggravating factor in Lafora rare disease
Neurodegenerative Lafora disease usually becomes apparent through seizures during adolescence and…Published: May 22, 2015
Researchers identify and correct premature aging in diseased cells.
Scientists from the Institut Pasteur, CNRS, Institut Gustave Roussy and CEA, have succeeded in…Published: May 22, 2015
Premature aging: Scientists identify and correct defects in diseased cells
(Institut Pasteur) Scientists from the Institut Pasteur and CNRS, in collaboration with scientists…Published: May 21, 2015
New cryptic amphipod discovered in West Caucasus caves
An international team of scientists have discovered a new species of typhlogammarid amphipod in the…Published: May 18, 2015
UCLA researchers deliver large particles into cells at high speed
UCLA engineers and doctors developed a tool that can deliver nanoparticles, enzymes, antibodies and…Published: Apr 08, 2015
Rare cause of anemia in newborns often overlooked, research suggests
Some babies diagnosed with and treated for a bone marrow failure disorder, called Diamond Blackfan…Published: Dec 07, 2013
New tool determines leukemia cells’ ‘readiness to die,’ may guide clinical care
Dana-Farber researchers have developed a method for determining how ready acute myeloid leukemia…Published: Oct 11, 2012
Dana-Farber Cancer Institute scientists target newly isolated ‘beige fat’ cells that could help fight obesity
Dana-Farber Cancer Institute researchers have isolated a new type of energy-burning fat cell called…Published: Jul 12, 2012
Blog Posts (Mitochondria)
A Dunning-Kruger manifesto about vaccines and autism [Respectful Insolence]
I’ve frequently written about the “arrogance of ignorance,” a phenomenon that…Published: May 29, 2015
Assistant Professor in Mitochondrial Biology and Metabolic Diseases
Max Planck Institute for Biology of Ageing – Karolinska Institutet Laboratory The newly…Posted: May 29, 2015